Bio Decontamination Solutions

Bio decontamination is defined as the process in which all types of microbiological contamination are reduced to populations that cannot be quantified by any method.

The objective of decontamination is to eliminate all forms of life from the environment, including bacteria, viruses, fungi, and eukaryotic cells. In short, the target is all life forms.

Decontamination can be performed using the following methods. The correct method depends on the area of application.

By temperature using an autoclave or high-temperature dry heat
By irradiation using gamma rays or X-rays
By chemicals such as ethylene oxide, formaldehyde, or hydrogen peroxide

Which Chemicals Are Used for Decontamination and What Are Their General Properties?

When selecting chemicals used in bio decontamination, safety is the primary concern. The following parameters influence chemical selection;

Permissible exposure limit; the time-weighted average concentration for users is 8 hours.
Short-term exposure limit; the average concentration limit for users is 30 minutes.
Ceiling limit; the level that must never be exceeded for humans under any circumstances.
Carcinogenicity level for humans
Chemical color
Flammability
Toxicity
Environmental friendliness

Chemicals Used for Decontamination

Chemicals	Properties
Ethylene Oxide	Widely used in pharmaceutical and hospital decontamination processes. Can only be used in airtight environments. Flammable, carcinogenic, and toxic.
Formaldehyde	Has long been used in pharmaceutical and hospital decontamination processes. Carcinogenic to humans. Leaves residues on surfaces.
Chlorine Dioxide (Green Gas)	Used in drinking water decontamination processes. Due to its toxicity, it can only be used in airtight environments. When decomposed by light and water, it produces toxic chlorine gas and highly corrosive hydrochloric acid.
Nitrogen Dioxide (Red Gas)	A relatively new method for decontamination. Can only be used in airtight environments. Toxic and polluting to the environment.
Ozone	Mainly used at low concentrations for farm disinfection. Toxic to humans. Becomes highly aggressive and corrosive on materials at high humidity.
Peracetic Acid	Commonly used in pharmaceutical and hospital decontamination processes. Flammable and highly reactive. At high concentrations, it becomes corrosive to many materials.
Hydrogen Peroxide (H₂O₂)	An old and well-known molecule. Decomposes into oxygen and water. Not carcinogenic to humans. Readily available on the market. Environmentally friendly. Highly compatible with materials.

Why VHP (Vaporized Hydrogen Peroxide)?

Because chemicals can be applied in aerosol or vapor form, depending on the area of application.

Aerosol, spray, dry fog, etc. are not easy to distribute, leave residues after evaporation, and pose potential compatibility risks. Their effectiveness depends on the treated surface and droplet size. They cannot pass through HEPA filters.

Vapor; is easy to distribute, leaves no residue, and has high material compatibility. Its effectiveness is time-dependent. It can pass through HEPA filters.

The vapor phase of hydrogen peroxide performs decontamination by utilizing all the properties of vapor.

Where Is Vaporized Hydrogen Peroxide Used?

VHP (vaporized hydrogen peroxide) is used where a 6-log reduction is required;

In the pharmaceutical industry,
In the food industry,
In hospitals,
In laboratory animal facilities,
In BSL-3 and BSL-4 laboratories,
For the decontamination of isolators and laboratory rooms.

For the Bioreset Series; you can review our products and request a presentation via the AMIRA link.

Devices Using Vaporized Hydrogen Peroxide

Depending on the area of use and the application surface, many brands offer decontamination devices and centralized management systems. Users can select the most suitable device for their needs with support from the manufacturer or product representative.

As Labor İldam Laboratory Equipment, the AMIRA brand we represent offers users multiple options for decontamination.

Our Most Frequently Preferred Bio Decontamination Solutions

Models	Features
Bioreset® Smart	The system can be placed directly inside the area to be treated. It can be equipped with a cart with an integrated scale for easy mobility in different areas. It operates independently or can be managed remotely via Modbus TCP/IP.
Bioreset® Plus	This generator can be used inside or outside the area to be decontaminated and can be easily moved thanks to its swivel wheels. When used externally, pass-through ports for inlet and outlet are required. It is CFR Part 21 compliant.
Bioreset® Pro	Bioreset® Pro is fully PLC-controlled via an Ethernet connection. With this remote control, it is possible to manage each component of the device, all functions, and all alarm signals. Control logic, cycle management, and related reporting are developed in cooperation with Amira. The generator is easy to maintain and can be adapted to all customer needs.
TURBOFLOW	This is an innovative ventilation system. It helps reduce cycle time by optimizing the distribution of the decontamination agent and simplifies the validation of cycle repeatability, even in rooms with complex geometries.
COMBO	Simultaneous decontamination of separate rooms. This is a perfectly customized solution for fast and effective decontamination cycles in complex areas and volumes up to 700 m³. It is an innovative system designed and customized to deliver the best results in production efficiency while meeting each customer’s specific requirements.

For more detailed information; you can review our products and request a presentation via the Bio Decontamination Solutions link.

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